HCSGD entry for PLA2G4B

1. General information

Official gene symbolPLA2G4B
Entrez ID100137049
Gene full namephospholipase A2, group IVB (cytosolic)
Other gene symbolsHsT16992 cPLA2-beta
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004622Lysophospholipase activityNASmolecular_function
GO:0005509Calcium ion bindingNASmolecular_function
GO:0005544Calcium-dependent phospholipid bindingNASmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006654Phosphatidic acid biosynthetic processTASbiological_process
GO:0006954Inflammatory responseNASbiological_process
GO:0006987Activation of signaling protein activity involved in unfolded protein responseTASbiological_process
GO:0007567ParturitionNASbiological_process
GO:0019369Arachidonic acid metabolic processNASbiological_process
GO:0019722Calcium-mediated signalingNASbiological_process
GO:0030968Endoplasmic reticulum unfolded protein responseTASbiological_process
GO:0031901Early endosome membraneIEAcellular_component
GO:0036148Phosphatidylglycerol acyl-chain remodelingTASbiological_process
GO:0036150Phosphatidylserine acyl-chain remodelingTASbiological_process
GO:0036151Phosphatidylcholine acyl-chain remodelingTASbiological_process
GO:0036152Phosphatidylethanolamine acyl-chain remodelingTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
GO:0046475Glycerophospholipid catabolic processIDAbiological_process
GO:0047498Calcium-dependent phospholipase A2 activityIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18188813120.99450495040.83562034901.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.1924470340
GSE28863_A2Up0.3695210359
GSE28863_A3Up0.0578205636
GSE28863_A4Up0.0235302905
GSE48662--

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-338-3pMIMAT0000763MIRT004685Immunoblot//Immunocytochemistry//Luciferase reporter assay//Microarray//qRT-PCRFunctional MTI18991333
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.