HCSGD entry for SLC12A6

1. General information

Official gene symbolSLC12A6
Entrez ID9990
Gene full namesolute carrier family 12 (potassium/chloride transporters), member 6
Other gene symbolsACCPN KCC3 KCC3A KCC3B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisNASbiological_process
GO:0005886Plasma membraneTAScellular_component
GO:0006811Ion transportIDA TASbiological_process
GO:0006813Potassium ion transportIEAbiological_process
GO:0006820Anion transportIDAbiological_process
GO:0006821Chloride transportIDAbiological_process
GO:0015379Potassium:chloride symporter activityIDA IEAmolecular_function
GO:0015698Inorganic anion transportIDAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0016323Basolateral plasma membraneISScellular_component
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0055085Transmembrane transportIEA TASbiological_process
GO:0071477Cellular hypotonic salinity responseIDAbiological_process
GO:1902476Chloride transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00092659470.99534460700.08295544221.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2010963444
GSE13712_SHEARUp0.0965407985
GSE13712_STATICDown-0.0186744680
GSE19018Up0.1748991109
GSE19899_A1Up0.2449573134
GSE19899_A2Up0.5262909391
PubMed_21979375_A1Up0.1897762529
PubMed_21979375_A2Up1.6756872975
GSE35957Up0.5070478867
GSE36640Down-0.1162872125
GSE54402Down-0.2179055743
GSE9593Up0.3874696728
GSE43922Up0.6936093191
GSE24585Up1.1021642103
GSE37065Up0.5366640022
GSE28863_A1Up0.9533242837
GSE28863_A2Up1.2917015933
GSE28863_A3Down-0.0862876619
GSE28863_A4Up0.6183663707
GSE48662Up0.5127958939

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Potassium ChlorideDB00761 APRD01322

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-652-3pMIMAT0003322MIRT039459CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.