HCSGD entry for NUP153
1. General information
| Official gene symbol | NUP153 |
|---|---|
| Entrez ID | 9972 |
| Gene full name | nucleoporin 153kDa |
| Other gene symbols | HNUP153 N153 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005215 | Transporter activity | TAS | molecular_function |
| GO:0005487 | Nucleocytoplasmic transporter activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005643 | Nuclear pore | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0007077 | Mitotic nuclear envelope disassembly | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008645 | Hexose transport | TAS | biological_process |
| GO:0010827 | Regulation of glucose transport | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0015758 | Glucose transport | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0017056 | Structural constituent of nuclear pore | IMP | molecular_function |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
| GO:0034399 | Nuclear periphery | IDA | cellular_component |
| GO:0042405 | Nuclear inclusion body | IDA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043495 | Protein anchor | IMP | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0044615 | Nuclear pore nuclear basket | IDA | cellular_component |
| GO:0046718 | Viral entry into host cell | IEA | biological_process |
| GO:0046832 | Negative regulation of RNA export from nucleus | IDA | biological_process |
| GO:0051028 | MRNA transport | IEA | biological_process |
| GO:0051292 | Nuclear pore complex assembly | IMP | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0075732 | Viral penetration into host nucleus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5453452300 | 0.4684230538 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0134714609 |
| GSE13712_SHEAR | Up | 0.4649345190 |
| GSE13712_STATIC | Up | 0.0968259617 |
| GSE19018 | Down | -0.1475172237 |
| GSE19899_A1 | Down | -0.0459563196 |
| GSE19899_A2 | Down | -0.0217026584 |
| PubMed_21979375_A1 | Up | 0.1141406750 |
| PubMed_21979375_A2 | Up | 0.1545488853 |
| GSE35957 | Down | -0.3177008655 |
| GSE36640 | Down | -0.2485060223 |
| GSE54402 | Up | 0.0042371375 |
| GSE9593 | Down | -0.2381889794 |
| GSE43922 | Up | 0.0108628937 |
| GSE24585 | Down | -0.0856490253 |
| GSE37065 | Up | 0.0632589336 |
| GSE28863_A1 | Up | 0.4933090590 |
| GSE28863_A2 | Up | 0.7913775204 |
| GSE28863_A3 | Down | -0.2515924759 |
| GSE28863_A4 | Down | -0.2601953130 |
| GSE48662 | Down | -0.1507419552 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016069 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030167 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037471 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038549 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-330-3p | MIMAT0000751 | MIRT043842 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048835 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050446 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052022 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 21811608 | We also found that Tpr depletion impairs the NES [nuclear export sequence]-dependent nuclear export of proteins and causes partial co-depletion of Nup153 |
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