HCSGD entry for THRAP3
1. General information
| Official gene symbol | THRAP3 |
|---|---|
| Entrez ID | 9967 |
| Gene full name | thyroid hormone receptor associated protein 3 |
| Other gene symbols | TRAP150 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000381 | Regulation of alternative mRNA splicing, via spliceosome | IMP | biological_process |
| GO:0000956 | Nuclear-transcribed mRNA catabolic process | IDA | biological_process |
| GO:0001104 | RNA polymerase II transcription cofactor activity | IDA | molecular_function |
| GO:0003712 | Transcription cofactor activity | IDA | molecular_function |
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0004872 | Receptor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | IDA | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0016592 | Mediator complex | IDA IEA | cellular_component |
| GO:0030374 | Ligand-dependent nuclear receptor transcription coactivator activity | NAS | molecular_function |
| GO:0030518 | Intracellular steroid hormone receptor signaling pathway | IDA | biological_process |
| GO:0030521 | Androgen receptor signaling pathway | IDA | biological_process |
| GO:0035145 | Exon-exon junction complex | IDA | cellular_component |
| GO:0042809 | Vitamin D receptor binding | NAS | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0046966 | Thyroid hormone receptor binding | IDA | molecular_function |
| GO:0048026 | Positive regulation of mRNA splicing, via spliceosome | IMP | biological_process |
| GO:0048255 | MRNA stabilization | IMP | biological_process |
| GO:0051219 | Phosphoprotein binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9634774401 | 0.1365487216 | 0.9999902473 | 0.7118437116 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0623404521 |
| GSE13712_SHEAR | Down | -0.0475657751 |
| GSE13712_STATIC | Up | 0.1035374285 |
| GSE19018 | Up | 0.0051550037 |
| GSE19899_A1 | Down | -0.1870099292 |
| GSE19899_A2 | Down | -0.5972529529 |
| PubMed_21979375_A1 | Down | -0.3661093773 |
| PubMed_21979375_A2 | Down | -0.3766641525 |
| GSE35957 | Down | -0.2556469473 |
| GSE36640 | Down | -0.3971390434 |
| GSE54402 | Up | 0.0665631957 |
| GSE9593 | Up | 0.1080239390 |
| GSE43922 | Down | -0.3046729985 |
| GSE24585 | Down | -0.0393547215 |
| GSE37065 | Up | 0.0222563421 |
| GSE28863_A1 | Down | -0.0081215463 |
| GSE28863_A2 | Down | -0.0465198229 |
| GSE28863_A3 | Down | -0.0317405533 |
| GSE28863_A4 | Down | -0.1138525965 |
| GSE48662 | Up | 0.1667998678 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-3p | MIMAT0004950 | MIRT037155 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037365 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040217 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-326 | MIMAT0000756 | MIRT043640 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045718 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046049 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
