HCSGD entry for GFPT2
1. General information
| Official gene symbol | GFPT2 |
|---|---|
| Entrez ID | 9945 |
| Gene full name | glutamine-fructose-6-phosphate transaminase 2 |
| Other gene symbols | GFAT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004360 | Glutamine-fructose-6-phosphate transaminase (isomerizing) activity | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006002 | Fructose 6-phosphate metabolic process | TAS | biological_process |
| GO:0006048 | UDP-N-acetylglucosamine biosynthetic process | IEA TAS | biological_process |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006488 | Dolichol-linked oligosaccharide biosynthetic process | TAS | biological_process |
| GO:0006541 | Glutamine metabolic process | IEA | biological_process |
| GO:0008152 | Metabolic process | IEA | biological_process |
| GO:0016051 | Carbohydrate biosynthetic process | IEA | biological_process |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0001038030 | 0.0476311804 | 0.0281262626 | 0.4089042074 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.0413373770 |
| GSE13712_SHEAR | Up | 0.6835326640 |
| GSE13712_STATIC | Up | 0.5832156383 |
| GSE19018 | Down | -1.4548257542 |
| GSE19899_A1 | Up | 3.7531190860 |
| GSE19899_A2 | Up | 2.8513061557 |
| PubMed_21979375_A1 | Up | 3.9334137274 |
| PubMed_21979375_A2 | Up | 3.4862562056 |
| GSE35957 | Down | -1.0087332114 |
| GSE36640 | Down | -2.7789489119 |
| GSE54402 | Up | 3.2524003422 |
| GSE9593 | Down | -0.5804282624 |
| GSE43922 | Up | 1.7095721076 |
| GSE24585 | Up | 0.5808316117 |
| GSE37065 | Up | 0.4596321069 |
| GSE28863_A1 | Up | 0.9842365783 |
| GSE28863_A2 | Up | 0.1433055794 |
| GSE28863_A3 | Down | -0.5720146530 |
| GSE28863_A4 | Down | -0.5499243080 |
| GSE48662 | Down | -0.4672384022 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021918 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022362 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023459 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027274 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028277 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045625 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
