HCSGD entry for EXOG
1. General information
| Official gene symbol | EXOG |
|---|---|
| Entrez ID | 9941 |
| Gene full name | endo/exonuclease (5'-3'), endonuclease G-like |
| Other gene symbols | ENDOGL1 ENDOGL2 ENGL ENGL-a ENGL-b ENGLA ENGLB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004519 | Endonuclease activity | NAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | NAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4814910756 | 0.6884058204 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1088396156 |
| GSE13712_SHEAR | Up | 0.2548047427 |
| GSE13712_STATIC | Up | 0.2569536748 |
| GSE19018 | Down | -0.3734684361 |
| GSE19899_A1 | Up | 0.0524552437 |
| GSE19899_A2 | Up | 0.1110721325 |
| PubMed_21979375_A1 | Up | 0.3165762762 |
| PubMed_21979375_A2 | Down | -0.0751031538 |
| GSE35957 | Down | -0.0779873122 |
| GSE36640 | Up | 0.4886014440 |
| GSE54402 | Up | 0.0126254546 |
| GSE9593 | Down | -0.0857382767 |
| GSE43922 | Up | 0.0481381029 |
| GSE24585 | Down | -0.0236528897 |
| GSE37065 | Down | -0.0473737417 |
| GSE28863_A1 | Up | 0.0568684348 |
| GSE28863_A2 | Down | -0.1514472652 |
| GSE28863_A3 | Down | -0.3931267498 |
| GSE28863_A4 | Down | -0.0837348817 |
| GSE48662 | Up | 0.1407679228 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042345 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23143977 | In particular, the tumor microenvironment, which is known to be critical during tumor initiation (Cancer Cell 7(5):411-423, 2005; J Clin Invest 121(6):2436-2446, 2011), prevention (Nature 410(6832):1107-1111, 2001), and progression (Cytokine Growth Factor Rev 21(1):3-10, 2010), also appears to dictate when oncogene inactivation elicits the permanent loss of self-renewal through induction of cellular senescence (Nat Rev Clin Oncol 8(3):151-160, 2011; Science 313(5795):1960-1964, 2006; N Engl J Med 351(21):2159-21569, 2004) |
Entries Per Page
Displaying Page of
