HCSGD entry for DENND4B


1. General information

Official gene symbolDENND4B
Entrez ID9909
Gene full nameDENN/MADD domain containing 4B
Other gene symbolsKIAA0476
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005794Golgi apparatusIDAcellular_component
GO:0017112Rab guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0032313Regulation of Rab GTPase activityIDAbiological_process
GO:0032318Regulation of Ras GTPase activityIDAbiological_process
GO:0032483Regulation of Rab protein signal transductionIDAbiological_process
GO:0043087Regulation of GTPase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92356430230.06548198400.99999024730.4832904428

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0120190647
GSE13712_SHEARDown-0.2466168964
GSE13712_STATICDown-0.1307314160
GSE19018Down-0.6436714818
GSE19899_A1Down-0.3214932923
GSE19899_A2Down-0.3689188197
PubMed_21979375_A1Down-0.0837744899
PubMed_21979375_A2Up0.3866126023
GSE35957Down-0.7560970263
GSE36640Down-0.6951569487
GSE54402Up0.1765960568
GSE9593Down-0.5752434424
GSE43922Up0.0467425781
GSE24585Down-0.0070703235
GSE37065Up0.0823992586
GSE28863_A1Up0.1865988600
GSE28863_A2Up0.4997005209
GSE28863_A3Down-0.0269137623
GSE28863_A4Down-0.1480985567
GSE48662Down-0.5480144714

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-501-3pMIMAT0004774MIRT037992CLASHFunctional MTI (Weak)23622248
hsa-miR-500a-3pMIMAT0002871MIRT041150CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041379CLASHFunctional MTI (Weak)23622248
hsa-miR-151a-3pMIMAT0000757MIRT043613CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044839CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049787CLASHFunctional MTI (Weak)23622248
hsa-miR-28-5pMIMAT0000085MIRT050007CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT051981CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.