HCSGD entry for CDC5L
1. General information
| Official gene symbol | CDC5L |
|---|---|
| Entrez ID | 988 |
| Gene full name | cell division cycle 5-like |
| Other gene symbols | CDC5 CDC5-LIKE CEF1 PCDC5RP dJ319D22.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0000974 | Prp19 complex | IDA | cellular_component |
| GO:0003677 | DNA binding | NAS | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
| GO:0071987 | WD40-repeat domain binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8322064511 | 0.1831523688 | 0.9999902473 | 0.8295910342 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0882715094 |
| GSE13712_SHEAR | Down | -0.1518734998 |
| GSE13712_STATIC | Up | 0.0214713410 |
| GSE19018 | Down | -0.0651555626 |
| GSE19899_A1 | Up | 0.0085923124 |
| GSE19899_A2 | Down | -0.2131781942 |
| PubMed_21979375_A1 | Down | -0.0224199899 |
| PubMed_21979375_A2 | Down | -0.3468519297 |
| GSE35957 | Down | -0.0614922946 |
| GSE36640 | Down | -0.5662224525 |
| GSE54402 | Up | 0.0627145184 |
| GSE9593 | Down | -0.1428359113 |
| GSE43922 | Down | -0.0648399694 |
| GSE24585 | Up | 0.2588882908 |
| GSE37065 | Up | 0.1268954382 |
| GSE28863_A1 | Up | 0.2060854453 |
| GSE28863_A2 | Up | 0.6673880950 |
| GSE28863_A3 | Down | -0.5861214935 |
| GSE28863_A4 | Down | -0.2154061557 |
| GSE48662 | Down | -0.4138059561 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025505 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031890 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038288 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-7-1-3p | MIMAT0004553 | MIRT038678 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT041014 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051492 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 16332694 | Furthermore, as part of our analysis of protein-protein interactions within the CDC5L complex, we found that SNEV interacts with itself |
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