HCSGD entry for DDX46
1. General information
| Official gene symbol | DDX46 |
|---|---|
| Entrez ID | 9879 |
| Gene full name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 |
| Other gene symbols | PRPF5 Prp5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0015030 | Cajal body | IEA | cellular_component |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8508351772 | 0.0288035827 | 0.9999902473 | 0.3223380527 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1942826465 |
| GSE13712_SHEAR | Down | -0.2614194569 |
| GSE13712_STATIC | Down | -0.2485307263 |
| GSE19018 | Down | -0.1047057950 |
| GSE19899_A1 | Down | -0.2185367531 |
| GSE19899_A2 | Down | -0.2931650882 |
| PubMed_21979375_A1 | Down | -0.3597553212 |
| PubMed_21979375_A2 | Down | -0.5164026174 |
| GSE35957 | Down | -0.6156906233 |
| GSE36640 | Down | -0.8156267805 |
| GSE54402 | Up | 0.3521312366 |
| GSE9593 | Down | -0.5092714201 |
| GSE43922 | Down | -0.0096112383 |
| GSE24585 | Down | -0.4412794490 |
| GSE37065 | Down | -0.1440067121 |
| GSE28863_A1 | Up | 0.8995598904 |
| GSE28863_A2 | Up | 0.8669376562 |
| GSE28863_A3 | Up | 0.1551227576 |
| GSE28863_A4 | Down | -0.1168312828 |
| GSE48662 | Down | -0.5421958196 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-5p | MIMAT0000093 | MIRT028028 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030807 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042512 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048690 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
