HCSGD entry for AREL1
1. General information
| Official gene symbol | AREL1 |
|---|---|
| Entrez ID | 9870 |
| Gene full name | apoptosis resistant E3 ubiquitin protein ligase 1 |
| Other gene symbols | KIAA0317 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IBA IDA IEA | molecular_function |
| GO:0005634 | Nucleus | IBA | cellular_component |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IBA IDA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2463376126 | 0.9267640363 | 0.9349738743 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0957320088 |
| GSE13712_SHEAR | Up | 0.0100878741 |
| GSE13712_STATIC | Up | 0.1066878620 |
| GSE19018 | Down | -0.0482561421 |
| GSE19899_A1 | Up | 0.0286090748 |
| GSE19899_A2 | Up | 0.1684892924 |
| PubMed_21979375_A1 | Down | -0.1699282568 |
| PubMed_21979375_A2 | Up | 0.2213640368 |
| GSE35957 | Up | 0.0132821342 |
| GSE36640 | Up | 0.0259685158 |
| GSE54402 | Up | 0.3164885112 |
| GSE9593 | Up | 0.0816405296 |
| GSE43922 | Up | 0.0552897654 |
| GSE24585 | Up | 0.1323691214 |
| GSE37065 | Up | 0.0991648303 |
| GSE28863_A1 | Up | 0.3231561360 |
| GSE28863_A2 | Up | 0.4319739696 |
| GSE28863_A3 | Down | -0.5723223825 |
| GSE28863_A4 | Down | -0.0077824192 |
| GSE48662 | Up | 0.1376479189 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-548b-3p | MIMAT0003254 | MIRT016243 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016609 | Microarray | Functional MTI (Weak) | 20304954 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
