HCSGD entry for PJA2
1. General information
| Official gene symbol | PJA2 |
|---|---|
| Entrez ID | 9867 |
| Gene full name | praja ring finger 2, E3 ubiquitin protein ligase |
| Other gene symbols | Neurodap1 RNF131 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007616 | Long-term memory | ISS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010738 | Regulation of protein kinase A signaling | IMP | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0034236 | Protein kinase A catalytic subunit binding | IMP | molecular_function |
| GO:0034237 | Protein kinase A regulatory subunit binding | IMP | molecular_function |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7646318415 | 0.0660200638 | 0.9999902473 | 0.4849885850 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1288331086 |
| GSE13712_SHEAR | Down | -0.2838939480 |
| GSE13712_STATIC | Down | -0.1079101771 |
| GSE19018 | Up | 0.6114098182 |
| GSE19899_A1 | Up | 0.0734590670 |
| GSE19899_A2 | Down | -0.5209691952 |
| PubMed_21979375_A1 | Down | -0.5546300101 |
| PubMed_21979375_A2 | Down | -0.5194414734 |
| GSE35957 | Up | 0.0701869187 |
| GSE36640 | Up | 0.2063758113 |
| GSE54402 | Down | -0.1635840164 |
| GSE9593 | Down | -0.1536058180 |
| GSE43922 | Down | -0.2882217113 |
| GSE24585 | Up | 0.4440741578 |
| GSE37065 | Up | 0.2178490843 |
| GSE28863_A1 | Down | -0.1193520078 |
| GSE28863_A2 | Up | 0.3130798896 |
| GSE28863_A3 | Down | -0.5339629609 |
| GSE28863_A4 | Down | -0.3741839551 |
| GSE48662 | Down | -0.2880088482 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017318 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028703 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT041028 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
