HCSGD entry for CEP350


1. General information

Official gene symbolCEP350
Entrez ID9857
Gene full namecentrosomal protein 350kDa
Other gene symbolsCAP350 GM133
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005819SpindleIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05150385620.65374649900.49800639001.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0707861937
GSE13712_SHEARUp0.1144731983
GSE13712_STATICDown-0.0126451968
GSE19018Up0.3742700177
GSE19899_A1Up0.0020303960
GSE19899_A2Down-0.3587431702
PubMed_21979375_A1Up0.2809802461
PubMed_21979375_A2Up0.1036813200
GSE35957Down-0.0660456592
GSE36640Down-0.3348910573
GSE54402Down-0.1337452320
GSE9593Up0.2234934742
GSE43922Up0.0010528811
GSE24585Up0.1706164495
GSE37065Up0.3501155297
GSE28863_A1Up1.2413667356
GSE28863_A2Up1.5662790054
GSE28863_A3Down-0.1315343925
GSE28863_A4Down-0.3843915275
GSE48662Up0.3999041705

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-19b-3pMIMAT0000074MIRT031197SequencingFunctional MTI (Weak)20371350
hsa-miR-1229-3pMIMAT0005584MIRT036285CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

24463355RESULTS: RNA-interference (21-mer siRNA) and pharmacological inhibition (CRT0066101) of PRKD2 profoundly inhibited proliferation of p53(wt) (U87MG, A172, and primary GBM2), and p53(mut) (GM133, T98G, U251, and primary Gli25) glioma cells
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