HCSGD entry for FARP2

1. General information

Official gene symbolFARP2
Entrez ID9855
Gene full nameFERM, RhoGEF and pleckstrin domain protein 2
Other gene symbolsFIR FRG PLEKHC3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIDA IEAmolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0007155Cell adhesionIEA ISSbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008092Cytoskeletal protein bindingIEAmolecular_function
GO:0016322Neuron remodelingIDAbiological_process
GO:0016601Rac protein signal transductionIDAbiological_process
GO:0019898Extrinsic component of membraneIEAcellular_component
GO:0030316Osteoclast differentiationIEA ISSbiological_process
GO:0030676Rac guanyl-nucleotide exchange factor activityIEA ISSmolecular_function
GO:0031532Actin cytoskeleton reorganizationIEA ISSbiological_process
GO:0032314Regulation of Rac GTPase activityISSbiological_process
GO:0032318Regulation of Ras GTPase activityIDA ISSbiological_process
GO:0032319Regulation of Rho GTPase activityIDA ISSbiological_process
GO:0033623Regulation of integrin activationIEA ISSbiological_process
GO:0043087Regulation of GTPase activityIDA ISSbiological_process
GO:0071526Semaphorin-plexin signaling pathwayIEA ISSbiological_process
GO:0071800Podosome assemblyIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35806392610.91117942330.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1191144723
GSE13712_SHEARUp0.1037196404
GSE13712_STATICUp0.0406545408
GSE19018Down-0.3013246634
GSE19899_A1Up0.1096383610
GSE19899_A2Up0.1876438983
PubMed_21979375_A1Up0.2356331047
PubMed_21979375_A2Up0.2433122482
GSE35957Up0.2446508240
GSE36640Down-0.0888213750
GSE54402Up0.1660354493
GSE9593Up0.0358019957
GSE43922Up0.1164262537
GSE24585Up0.1139663716
GSE37065Down-0.0640009052
GSE28863_A1Up0.0735436840
GSE28863_A2Up0.3158624833
GSE28863_A3Up0.0647234910
GSE28863_A4Down-0.1468090423
GSE48662Up0.0886229727

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.