HCSGD entry for PLEKHM1
1. General information
| Official gene symbol | PLEKHM1 |
|---|---|
| Entrez ID | 9842 |
| Gene full name | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| Other gene symbols | AP162 B2 OPTB6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0121499639 | 0.9926099464 | 0.2756139535 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2278327729 |
| GSE13712_SHEAR | Up | 0.1958279809 |
| GSE13712_STATIC | Up | 0.2109657816 |
| GSE19018 | Down | -0.0417632962 |
| GSE19899_A1 | Down | -0.0249701039 |
| GSE19899_A2 | Up | 0.5439687816 |
| PubMed_21979375_A1 | Up | 0.4323964543 |
| PubMed_21979375_A2 | Up | 0.6018156859 |
| GSE35957 | Up | 0.3284992117 |
| GSE36640 | Up | 0.4690899550 |
| GSE54402 | Up | 0.4315755728 |
| GSE9593 | Up | 0.4195490772 |
| GSE43922 | Up | 0.8059746378 |
| GSE24585 | Up | 0.6626529254 |
| GSE37065 | Down | -0.0144630516 |
| GSE28863_A1 | Up | 0.2599347623 |
| GSE28863_A2 | Up | 0.5737779980 |
| GSE28863_A3 | Down | -0.1024485115 |
| GSE28863_A4 | Down | -0.0969953065 |
| GSE48662 | Up | 0.0584466917 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044379 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047158 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051055 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3909 | MIMAT0018183 | MIRT052883 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
