HCSGD entry for CDK11B

1. General information

Official gene symbolCDK11B
Entrez ID984
Gene full namecyclin-dependent kinase 11B
Other gene symbolsCDC2L1 CDK11 CDK11-p110 CDK11-p46 CDK11-p58 CLK-1 PK58 p58 p58CDC2L1 p58CLK-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthIEPbiological_process
GO:0001824Blastocyst developmentIEAbiological_process
GO:0004672Protein kinase activityTASmolecular_function
GO:0004674Protein serine/threonine kinase activityIDA IEAmolecular_function
GO:0004693Cyclin-dependent protein serine/threonine kinase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006468Protein phosphorylationIDAbiological_process
GO:0006915Apoptotic processNASbiological_process
GO:0007067MitosisNASbiological_process
GO:0007088Regulation of mitosisIEAbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0050684Regulation of mRNA processingIDAbiological_process
GO:2001234Negative regulation of apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25492229780.99120539110.94633329571.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.0323776618
GSE24585Up0.2718088937
GSE37065Up0.0325313727
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.1565008008

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.