HCSGD entry for IST1
1. General information
| Official gene symbol | IST1 |
|---|---|
| Entrez ID | 9798 |
| Gene full name | increased sodium tolerance 1 homolog (yeast) |
| Other gene symbols | OLC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000910 | Cytokinesis | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005793 | Endoplasmic reticulum-Golgi intermediate compartment | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0008104 | Protein localization | IMP | biological_process |
| GO:0009838 | Abscission | IDA IMP | biological_process |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0019076 | Viral release from host cell | IDA | biological_process |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0032403 | Protein complex binding | IDA | molecular_function |
| GO:0045862 | Positive regulation of proteolysis | IDA | biological_process |
| GO:0046745 | Viral capsid secondary envelopment | IDA | biological_process |
| GO:0048672 | Positive regulation of collateral sprouting | IEA | biological_process |
| GO:0051301 | Cell division | IMP | biological_process |
| GO:0070062 | Extracellular vesicular exosome | IDA | cellular_component |
| GO:0090541 | MIT domain binding | IPI | molecular_function |
| GO:0090543 | Flemming body | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2576063371 | 0.8560840318 | 0.9512200028 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1141369145 |
| GSE13712_SHEAR | Up | 0.1018177035 |
| GSE13712_STATIC | Up | 0.2749679869 |
| GSE19018 | Up | 0.0038916204 |
| GSE19899_A1 | Up | 0.0827906467 |
| GSE19899_A2 | Down | -0.1376115481 |
| PubMed_21979375_A1 | Down | -0.2709415517 |
| PubMed_21979375_A2 | Up | 0.0863164485 |
| GSE35957 | Down | -0.0312310684 |
| GSE36640 | Up | 0.2479553570 |
| GSE54402 | Down | -0.3203111538 |
| GSE9593 | Down | -0.0298300299 |
| GSE43922 | Up | 0.2098320398 |
| GSE24585 | Up | 0.3378451540 |
| GSE37065 | Up | 0.1536938045 |
| GSE28863_A1 | Up | 0.2083054045 |
| GSE28863_A2 | Up | 0.1243765138 |
| GSE28863_A3 | Down | -0.5072343794 |
| GSE28863_A4 | Up | 0.1561157523 |
| GSE48662 | Up | 0.1739366971 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023986 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
