HCSGD entry for SPCS2
1. General information
| Official gene symbol | SPCS2 |
|---|---|
| Entrez ID | 9789 |
| Gene full name | signal peptidase complex subunit 2 homolog (S. cerevisiae) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005787 | Signal peptidase complex | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006465 | Signal peptide processing | IEA | biological_process |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0008233 | Peptidase activity | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4564122146 | 0.4423657384 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2407479532 |
| GSE13712_SHEAR | Down | -0.1687078512 |
| GSE13712_STATIC | Up | 0.0049998544 |
| GSE19018 | Down | -0.4201233077 |
| GSE19899_A1 | Down | -0.0561307913 |
| GSE19899_A2 | Down | -0.1618030913 |
| PubMed_21979375_A1 | Up | 0.1642113320 |
| PubMed_21979375_A2 | Down | -0.3105847615 |
| GSE35957 | Up | 0.2984443995 |
| GSE36640 | Up | 0.1371050943 |
| GSE54402 | Up | 0.1657706198 |
| GSE9593 | Down | -0.1197266632 |
| GSE43922 | Up | 0.0957959526 |
| GSE24585 | Down | -0.0587748285 |
| GSE37065 | Up | 0.0450613433 |
| GSE28863_A1 | Up | 0.3281331879 |
| GSE28863_A2 | Up | 0.4623923856 |
| GSE28863_A3 | Up | 0.0188159472 |
| GSE28863_A4 | Down | -0.3206007375 |
| GSE48662 | Down | -0.1881465792 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7e-5p | MIMAT0000066 | MIRT051434 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
