HCSGD entry for DHX38
1. General information
| Official gene symbol | DHX38 |
|---|---|
| Entrez ID | 9785 |
| Gene full name | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| Other gene symbols | DDX38 PRP16 PRPF16 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IC IDA TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2772298317 | 0.4912230462 | 0.9740977707 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0282950753 |
| GSE13712_SHEAR | Down | -0.1027913855 |
| GSE13712_STATIC | Down | -0.3395383654 |
| GSE19018 | Down | -0.2370357205 |
| GSE19899_A1 | Up | 0.0119953453 |
| GSE19899_A2 | Up | 0.0796006866 |
| PubMed_21979375_A1 | Up | 1.3090831760 |
| PubMed_21979375_A2 | Down | -0.2317365956 |
| GSE35957 | Down | -0.3963593055 |
| GSE36640 | Down | -0.5668940792 |
| GSE54402 | Up | 0.3760392660 |
| GSE9593 | Down | -0.2637785687 |
| GSE43922 | Up | 0.1585319363 |
| GSE24585 | Down | -0.1711390756 |
| GSE37065 | Down | -0.0775211124 |
| GSE28863_A1 | Up | 0.2890507701 |
| GSE28863_A2 | Up | 0.2539972141 |
| GSE28863_A3 | Up | 0.3538273546 |
| GSE28863_A4 | Up | 0.1028559324 |
| GSE48662 | Up | 0.1395912488 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025390 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-484 | MIMAT0002174 | MIRT041970 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046022 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051303 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
