HCSGD entry for CDA


1. General information

Official gene symbolCDA
Entrez ID978
Gene full namecytidine deaminase
Other gene symbolsCDD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001882Nucleoside bindingIDAmolecular_function
GO:0004126Cytidine deaminase activityEXP IDAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005829CytosolNAS TAScellular_component
GO:0006206Pyrimidine nucleobase metabolic processTASbiological_process
GO:0007166Cell surface receptor signaling pathwayNASbiological_process
GO:0008270Zinc ion bindingIDA TASmolecular_function
GO:0008655Pyrimidine-containing compound salvageNASbiological_process
GO:0009972Cytidine deaminationIDAbiological_process
GO:0019858Cytosine metabolic processTASbiological_process
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043097Pyrimidine nucleoside salvageTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045980Negative regulation of nucleotide metabolic processIDAbiological_process
GO:0051289Protein homotetramerizationIDAbiological_process
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09299785720.29752781050.63959057441.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1130827569
GSE13712_SHEARUp0.3671372734
GSE13712_STATICDown-0.2031926331
GSE19018Down-0.1084549719
GSE19899_A1Up0.1570305350
GSE19899_A2Up0.7759962284
PubMed_21979375_A1Up0.3138660848
PubMed_21979375_A2Up0.8498152130
GSE35957Up1.3446273219
GSE36640Down-0.1373035299
GSE54402Up0.0511093127
GSE9593Down-0.0159146601
GSE43922Up0.0513468139
GSE24585Down-0.1291117964
GSE37065Up0.3113700464
GSE28863_A1Down-0.4994177579
GSE28863_A2Down-0.3728426921
GSE28863_A3Down-0.0688333137
GSE28863_A4Down-0.2266682366
GSE48662Up0.2044794862

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

1-Beta-Ribofuranosyl-1,3-DiazepinoneDB03185 EXPT00750
DN-101DB05314 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018180MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.