HCSGD entry for BCLAF1
1. General information
| Official gene symbol | BCLAF1 |
|---|---|
| Entrez ID | 9774 |
| Gene full name | BCL2-associated transcription factor 1 |
| Other gene symbols | BTF bK211L9.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA TAS | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IDA | biological_process |
| GO:0043620 | Regulation of DNA-templated transcription in response to stress | IMP | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA IEA TAS | biological_process |
| GO:2000144 | Positive regulation of DNA-templated transcription, initiation | IMP | biological_process |
| GO:2001022 | Positive regulation of response to DNA damage stimulus | IEA IMP | biological_process |
| GO:2001244 | Positive regulation of intrinsic apoptotic signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9567169029 | 0.0377117473 | 0.9999902473 | 0.3662703430 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1438831137 |
| GSE13712_SHEAR | Up | 0.0337848153 |
| GSE13712_STATIC | Up | 0.0396725764 |
| GSE19018 | Down | -0.3823348638 |
| GSE19899_A1 | Down | -0.2009589009 |
| GSE19899_A2 | Down | -0.6620458682 |
| PubMed_21979375_A1 | Down | -0.3816654469 |
| PubMed_21979375_A2 | Down | -0.3549401090 |
| GSE35957 | Up | 0.2562909551 |
| GSE36640 | Down | -0.5019071363 |
| GSE54402 | Down | -0.2113762848 |
| GSE9593 | Down | -0.1929920752 |
| GSE43922 | Down | -0.1440674462 |
| GSE24585 | Down | -0.5336010177 |
| GSE37065 | Up | 0.0504151365 |
| GSE28863_A1 | Up | 0.3652289924 |
| GSE28863_A2 | Up | 0.3002262699 |
| GSE28863_A3 | Down | -0.2429595175 |
| GSE28863_A4 | Down | -0.0440374534 |
| GSE48662 | Down | -0.2767875068 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025263 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037120 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038025 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-5p | MIMAT0004694 | MIRT038219 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-22-5p | MIMAT0004495 | MIRT038963 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040388 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT050044 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
