HCSGD entry for CD81
1. General information
| Official gene symbol | CD81 |
|---|---|
| Entrez ID | 975 |
| Gene full name | CD81 molecule |
| Other gene symbols | CVID6 S5.7 TAPA1 TSPAN28 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000187 | Activation of MAPK activity | IDA | biological_process |
| GO:0001772 | Immunological synapse | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0006661 | Phosphatidylinositol biosynthetic process | IDA | biological_process |
| GO:0008104 | Protein localization | IDA | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0023026 | MHC class II protein complex binding | IDA | molecular_function |
| GO:0043128 | Positive regulation of 1-phosphatidylinositol 4-kinase activity | IDA | biological_process |
| GO:0046488 | Phosphatidylinositol metabolic process | IDA | biological_process |
| GO:0046718 | Viral entry into host cell | TAS | biological_process |
| GO:0046813 | Receptor-mediated virion attachment to host cell | TAS | biological_process |
| GO:0050731 | Positive regulation of peptidyl-tyrosine phosphorylation | IDA | biological_process |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1752660803 | 0.5423938072 | 0.8224600642 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0709691956 |
| GSE13712_SHEAR | Down | -0.0927155907 |
| GSE13712_STATIC | Up | 0.0254729936 |
| GSE19018 | Up | 0.7590097942 |
| GSE19899_A1 | Down | -0.2739631749 |
| GSE19899_A2 | Up | 0.6306687231 |
| PubMed_21979375_A1 | Down | -0.5464131892 |
| PubMed_21979375_A2 | Down | -0.1236251312 |
| GSE35957 | Down | -0.0335261087 |
| GSE36640 | Up | 0.5455722076 |
| GSE54402 | Down | -0.3060957512 |
| GSE9593 | Up | 0.2388420340 |
| GSE43922 | Up | 0.0025477717 |
| GSE24585 | Down | -0.4195365030 |
| GSE37065 | Up | 0.0975179032 |
| GSE28863_A1 | Up | 0.2566909390 |
| GSE28863_A2 | Up | 0.2868061795 |
| GSE28863_A3 | Down | -0.0865042404 |
| GSE28863_A4 | Up | 0.0616363606 |
| GSE48662 | Up | 0.3403148639 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020808 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038125 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039120 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052151 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052737 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
