HCSGD entry for ECE2
1. General information
| Official gene symbol | ECE2 |
|---|---|
| Entrez ID | 9718 |
| Gene full name | endothelin converting enzyme 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0004222 | Metalloendopeptidase activity | IDA IEA | molecular_function |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0007420 | Brain development | ISS | biological_process |
| GO:0007507 | Heart development | ISS | biological_process |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
| GO:0010002 | Cardioblast differentiation | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016486 | Peptide hormone processing | IDA | biological_process |
| GO:0030659 | Cytoplasmic vesicle membrane | IDA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2467531097 | 0.8265933209 | 0.9349738743 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1380858367 |
| GSE13712_SHEAR | Down | -0.2677257341 |
| GSE13712_STATIC | Up | 0.1646236723 |
| GSE19018 | Up | 0.0373215146 |
| GSE19899_A1 | Up | 0.0715800727 |
| GSE19899_A2 | Up | 0.5010055247 |
| PubMed_21979375_A1 | Up | 1.1018631989 |
| PubMed_21979375_A2 | Up | 0.8205779431 |
| GSE35957 | Down | -0.1213584756 |
| GSE36640 | Up | 0.0206586898 |
| GSE54402 | Up | 0.3491556061 |
| GSE9593 | Down | -0.2026589872 |
| GSE43922 | Up | 0.1766975458 |
| GSE24585 | Down | -0.2913096027 |
| GSE37065 | Down | -0.2035752998 |
| GSE28863_A1 | Down | -0.1087521703 |
| GSE28863_A2 | Up | 0.0367570118 |
| GSE28863_A3 | Up | 0.0966965586 |
| GSE28863_A4 | Down | -0.0123110219 |
| GSE48662 | Down | -0.0811923483 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023101 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
