HCSGD entry for HERPUD1

1. General information

Official gene symbolHERPUD1
Entrez ID9709
Gene full namehomocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Other gene symbolsHERP Mif1 SUP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005789Endoplasmic reticulum membraneIDA TAScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0006874Cellular calcium ion homeostasisIEAbiological_process
GO:0006986Response to unfolded proteinIEPbiological_process
GO:0006987Activation of signaling protein activity involved in unfolded protein responseTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030968Endoplasmic reticulum unfolded protein responseTASbiological_process
GO:0031396Regulation of protein ubiquitinationIEAbiological_process
GO:0032092Positive regulation of protein bindingIEAbiological_process
GO:0043154Negative regulation of cysteine-type endopeptidase activity involved in apoptotic processIEAbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16695013110.89915714450.80682820181.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1502023698
GSE13712_SHEARUp0.0492528343
GSE13712_STATICDown-0.1098215864
GSE19018Up0.2311825854
GSE19899_A1Up0.3889363884
GSE19899_A2Down-0.0255924388
PubMed_21979375_A1Up0.2641664430
PubMed_21979375_A2Down-0.0559384560
GSE35957Up0.5854895531
GSE36640Up0.2655618745
GSE54402Up0.0757524239
GSE9593Up0.0309194038
GSE43922Down-0.0238546045
GSE24585Up0.4239140990
GSE37065Down-0.1832020416
GSE28863_A1Up0.1072573448
GSE28863_A2Up0.1215898986
GSE28863_A3Down-0.1868042056
GSE28863_A4Up0.0110037896
GSE48662Up0.3239926542

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-373-3pMIMAT0000726MIRT002508Microarray//Microarray;OtherFunctional MTI (Weak)15685193
hsa-miR-335-5pMIMAT0000765MIRT018664MicroarrayFunctional MTI (Weak)18185580
hsa-miR-375MIMAT0000728MIRT019938MicroarrayFunctional MTI (Weak)20215506
hsa-miR-26b-5pMIMAT0000083MIRT029926MicroarrayFunctional MTI (Weak)19088304
hsa-miR-615-3pMIMAT0003283MIRT039770CLASHFunctional MTI (Weak)23622248
hsa-miR-93-5pMIMAT0000093MIRT048869CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-373-3pMIMAT0000726NAhsa-miR-37315685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23634235Amongst the genes were IRAK3, SelS, HSPA5, HERPUD1, DNAJB9, SEPR1, C18orf55, ARF4, RINT1, NXT1, CADPS2, COG6, and GLRX5
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