HCSGD entry for ULK2
1. General information
| Official gene symbol | ULK2 |
|---|---|
| Entrez ID | 9706 |
| Gene full name | unc-51-like kinase 2 (C. elegans) |
| Other gene symbols | ATG1B Unc51.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006914 | Autophagy | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0010506 | Regulation of autophagy | IDA | biological_process |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0034045 | Pre-autophagosomal structure membrane | IDA | cellular_component |
| GO:0042594 | Response to starvation | ISS | biological_process |
| GO:0046777 | Protein autophosphorylation | IDA | biological_process |
| GO:0048671 | Negative regulation of collateral sprouting | IEA | biological_process |
| GO:0048675 | Axon extension | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9196046465 | 0.0271276775 | 0.9999902473 | 0.3141081722 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3951582347 |
| GSE13712_SHEAR | Down | -0.4208015415 |
| GSE13712_STATIC | Up | 0.0435100342 |
| GSE19018 | Down | -0.1229596858 |
| GSE19899_A1 | Down | -0.2287647787 |
| GSE19899_A2 | Down | -0.7293202902 |
| PubMed_21979375_A1 | Down | -0.2468445818 |
| PubMed_21979375_A2 | Down | -0.2222554707 |
| GSE35957 | Up | 0.2334784078 |
| GSE36640 | Down | -0.0478732110 |
| GSE54402 | Down | -0.7687087390 |
| GSE9593 | Up | 0.0431520278 |
| GSE43922 | Down | -0.6785539621 |
| GSE24585 | Up | 0.2220606971 |
| GSE37065 | Down | -0.5469208234 |
| GSE28863_A1 | Up | 0.5994233202 |
| GSE28863_A2 | Up | 0.0687923880 |
| GSE28863_A3 | Down | -0.2289663371 |
| GSE28863_A4 | Down | -0.1340079941 |
| GSE48662 | Up | 0.1965576569 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016824 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
