HCSGD entry for CEP57
1. General information
| Official gene symbol | CEP57 |
|---|---|
| Entrez ID | 9702 |
| Gene full name | centrosomal protein 57kDa |
| Other gene symbols | MVA2 PIG8 TSP57 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000060 | Protein import into nucleus, translocation | IEA ISS | biological_process |
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA ISS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0007286 | Spermatid development | IEA ISS | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | IPI | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0017134 | Fibroblast growth factor binding | IPI | molecular_function |
| GO:0034453 | Microtubule anchoring | IEA | biological_process |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043015 | Gamma-tubulin binding | IEA | molecular_function |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9843850272 | 0.0010645492 | 0.9999902473 | 0.0622263858 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3731338707 |
| GSE13712_SHEAR | Down | -0.5957299605 |
| GSE13712_STATIC | Down | -0.5965565384 |
| GSE19018 | Up | 0.4752457492 |
| GSE19899_A1 | Down | -0.9212084730 |
| GSE19899_A2 | Down | -2.4713098258 |
| PubMed_21979375_A1 | Down | -1.8595014652 |
| PubMed_21979375_A2 | Down | -2.7031142232 |
| GSE35957 | Down | -0.7264120928 |
| GSE36640 | Down | -1.5507728084 |
| GSE54402 | Down | -0.5640287478 |
| GSE9593 | Down | -0.3993327742 |
| GSE43922 | Down | -1.2871569466 |
| GSE24585 | Up | 0.3176028240 |
| GSE37065 | Down | -0.1129688514 |
| GSE28863_A1 | Up | 0.0880915071 |
| GSE28863_A2 | Up | 0.0248844459 |
| GSE28863_A3 | Down | -0.4070979012 |
| GSE28863_A4 | Up | 0.0593589941 |
| GSE48662 | Down | -0.3359546916 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT039373 | CLASH | Functional MTI (Weak) | 23622248 |
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