HCSGD entry for CD70


1. General information

Official gene symbolCD70
Entrez ID970
Gene full nameCD70 molecule
Other gene symbolsCD27L CD27LG TNFSF7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002020Protease bindingIPImolecular_function
GO:0005102Receptor bindingTASmolecular_function
GO:0005125Cytokine activityIEAmolecular_function
GO:0005164Tumor necrosis factor receptor bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0097191Extrinsic apoptotic signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74658473460.24585483450.99999024730.9543054269

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1008740275
GSE13712_SHEARDown-0.1637256054
GSE13712_STATICUp0.0298543435
GSE19018Up0.0442658384
GSE19899_A1Up0.0860109251
GSE19899_A2Up0.4756452509
PubMed_21979375_A1Down-0.1046926544
PubMed_21979375_A2Up0.0528720042
GSE35957Down-1.0134737526
GSE36640Down-0.1193767700
GSE54402Down-0.0759113808
GSE9593Down-0.0667472696
GSE43922Up0.0235568638
GSE24585Up0.0509841906
GSE37065Up0.3050419695
GSE28863_A1Down-0.5799581338
GSE28863_A2Down-0.4588596607
GSE28863_A3Up0.1297621579
GSE28863_A4Up0.1256065657
GSE48662Up0.0626887292

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.