HCSGD entry for RIMS2


1. General information

Official gene symbolRIMS2
Entrez ID9699
Gene full nameregulating synaptic membrane exocytosis 2
Other gene symbolsOBOE RAB3IP3 RIM2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0006886Intracellular protein transportIEAbiological_process
GO:0017137Rab GTPase bindingIEAmolecular_function
GO:0017156Calcium ion-dependent exocytosisIEAbiological_process
GO:0017157Regulation of exocytosisIEAbiological_process
GO:0019933CAMP-mediated signalingIEAbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030073Insulin secretionIEAbiological_process
GO:0042391Regulation of membrane potentialIEAbiological_process
GO:0042734Presynaptic membraneIEAcellular_component
GO:0044325Ion channel bindingIEAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048791Calcium ion-dependent exocytosis of neurotransmitterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47461069110.70283041300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0559776956
GSE13712_SHEARDown-0.5239510000
GSE13712_STATICDown-0.3914141719
GSE19018Up0.0960263500
GSE19899_A1Up0.0674718910
GSE19899_A2Up0.3533724434
PubMed_21979375_A1Up0.1633301638
PubMed_21979375_A2Up0.0904633926
GSE35957Up0.2518450094
GSE36640Up0.4819083558
GSE54402Down-0.0128576633
GSE9593Up0.0500760994
GSE43922Up0.2313912689
GSE24585Down-0.2024800338
GSE37065Down-0.0694424650
GSE28863_A1Down-0.0519596471
GSE28863_A2Up0.0437278229
GSE28863_A3Up0.1285134159
GSE28863_A4Down-0.0790648325
GSE48662Up0.0461239363

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023538MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.