HCSGD entry for CD69


1. General information

Official gene symbolCD69
Entrez ID969
Gene full nameCD69 molecule
Other gene symbolsAIM BL-AC/P26 CLEC2C EA1 GP32/28 MLR-3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004888Transmembrane signaling receptor activityTASmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0035690Cellular response to drugIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00098194600.30010685000.08529967001.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3028117265
GSE13712_SHEARUp0.3745874960
GSE13712_STATICUp1.7559094246
GSE19018Down-1.3508478666
GSE19899_A1Up0.9166078924
GSE19899_A2Up2.2726229044
PubMed_21979375_A1Up1.1787088649
PubMed_21979375_A2Up2.5206986880
GSE35957Down-0.0836334132
GSE36640Up1.5229048375
GSE54402Up2.7735752167
GSE9593Up0.0586591919
GSE43922Up2.5327245729
GSE24585Up0.1400732145
GSE37065Down-0.0421701494
GSE28863_A1Down-0.9806245334
GSE28863_A2Down-1.1829890202
GSE28863_A3Up0.1881341669
GSE28863_A4Up0.0387103345
GSE48662Up0.0263221632

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016695MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

27853638Remarkably, NK cell population was not affected by the melphalan dose used, but rather displayed activation features as indicated by CD107a and CD69 expression
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