HCSGD entry for DEPDC5


1. General information

Official gene symbolDEPDC5
Entrez ID9681
Gene full nameDEP domain containing 5
Other gene symbolsDEP.5 FFEVF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005096GTPase activator activityIEAmolecular_function
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005829CytosolIEA ISScellular_component
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88298501960.24468707500.99999024730.9524413635

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0248868951
GSE13712_SHEARUp0.0571400545
GSE13712_STATICUp0.1534380774
GSE19018Down-0.3615064110
GSE19899_A1Down-0.1346582850
GSE19899_A2Down-0.2177644155
PubMed_21979375_A1Up0.4603118513
PubMed_21979375_A2Up0.1211012210
GSE35957Down-0.0731068676
GSE36640Down-0.2941952015
GSE54402Down-0.2547248659
GSE9593Down-0.0686934829
GSE43922Down-0.0411394415
GSE24585Down-0.0143673134
GSE37065Up0.0898722202
GSE28863_A1Down-0.0742989793
GSE28863_A2Up0.1325158004
GSE28863_A3Down-0.2874426561
GSE28863_A4Down-0.0232731369
GSE48662Down-0.1006175738

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017533MicroarrayFunctional MTI (Weak)18185580
hsa-miR-331-3pMIMAT0000760MIRT043372CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.