HCSGD entry for PPM1F

1. General information

Official gene symbolPPM1F
Entrez ID9647
Gene full nameprotein phosphatase, Mg2+/Mn2+ dependent, 1F
Other gene symbolsCAMKP CaMKPase FEM-2 POPX2 hFEM-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004722Protein serine/threonine phosphatase activityIDA IEA IMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolIDA IEAcellular_component
GO:0006469Negative regulation of protein kinase activityIDAbiological_process
GO:0006470Protein dephosphorylationIEAbiological_process
GO:0010628Positive regulation of gene expressionIMPbiological_process
GO:0010634Positive regulation of epithelial cell migrationIMPbiological_process
GO:0010811Positive regulation of cell-substrate adhesionIMPbiological_process
GO:0016301Kinase activityIEAmolecular_function
GO:0016576Histone dephosphorylationIEAbiological_process
GO:0016791Phosphatase activityIDAmolecular_function
GO:0033137Negative regulation of peptidyl-serine phosphorylationIDAbiological_process
GO:0033192Calmodulin-dependent protein phosphatase activityIDAmolecular_function
GO:0035690Cellular response to drugIDAbiological_process
GO:0035970Peptidyl-threonine dephosphorylationIDAbiological_process
GO:0043234Protein complexIDAcellular_component
GO:0043280Positive regulation of cysteine-type endopeptidase activity involved in apoptotic processIDA IEAbiological_process
GO:0044387Negative regulation of protein kinase activity by regulation of protein phosphorylationIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIMPbiological_process
GO:0045927Positive regulation of growthIMPbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0050921Positive regulation of chemotaxisIMPbiological_process
GO:0051496Positive regulation of stress fiber assemblyIDA IMPbiological_process
GO:0051894Positive regulation of focal adhesion assemblyIMPbiological_process
GO:0097193Intrinsic apoptotic signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23270477950.81889101100.91650793061.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1862320945
GSE13712_SHEARUp0.1787667849
GSE13712_STATICUp0.0932308162
GSE19018Down-0.0767875875
GSE19899_A1Up0.0814283428
GSE19899_A2Up0.5653293848
PubMed_21979375_A1Up0.0686220997
PubMed_21979375_A2Up0.4244671080
GSE35957Down-0.0876457906
GSE36640Up0.3403047393
GSE54402Up0.1883722194
GSE9593Up0.0684796119
GSE43922Up0.0339220000
GSE24585Down-0.5693810315
GSE37065Down-0.1376482619
GSE28863_A1Down-0.0456899161
GSE28863_A2Up0.0840477581
GSE28863_A3Up0.0474304711
GSE28863_A4Up0.1648849311
GSE48662Down-0.0737066044

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-24-3pMIMAT0000080MIRT030441MicroarrayFunctional MTI (Weak)19748357
hsa-miR-324-5pMIMAT0000761MIRT043063CLASHFunctional MTI (Weak)23622248
hsa-miR-186-5pMIMAT0000456MIRT045175CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.