HCSGD entry for CTR9

1. General information

Official gene symbolCTR9
Entrez ID9646
Gene full nameCtr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Other gene symbolsSH2BP1 TSBP p150 p150TSP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0001711Endodermal cell fate commitmentISSbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007259JAK-STAT cascadeISSbiological_process
GO:0010390Histone monoubiquitinationIDAbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0016593Cdc73/Paf1 complexIDAcellular_component
GO:0016607Nuclear speckIEAcellular_component
GO:0019827Stem cell maintenanceIDAbiological_process
GO:0032968Positive regulation of transcription elongation from RNA polymerase II promoterIDAbiological_process
GO:0033523Histone H2B ubiquitinationIDAbiological_process
GO:0035327Transcriptionally active chromatinISScellular_component
GO:0042169SH2 domain bindingIEAmolecular_function
GO:0045638Negative regulation of myeloid cell differentiationIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0051571Positive regulation of histone H3-K4 methylationIMPbiological_process
GO:0070102Interleukin-6-mediated signaling pathwayISSbiological_process
GO:0071222Cellular response to lipopolysaccharideISSbiological_process
GO:0080182Histone H3-K4 trimethylationIMPbiological_process
GO:2001162Positive regulation of histone H3-K79 methylationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06003097910.90129858290.53129788161.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1874872835
GSE13712_SHEARUp0.0692877963
GSE13712_STATICUp0.0527598488
GSE19018Down-0.4757691878
GSE19899_A1Up0.1024825672
GSE19899_A2Up0.1914640799
PubMed_21979375_A1Down-0.3418682717
PubMed_21979375_A2Up0.5449725770
GSE35957Up0.3036627266
GSE36640Up0.2481273964
GSE54402Down-0.0693455665
GSE9593Up0.0640234029
GSE43922Down-0.0508122361
GSE24585Up0.2551830980
GSE37065Up0.0244370792
GSE28863_A1Up1.0123151529
GSE28863_A2Up0.9860590372
GSE28863_A3Up0.0862759682
GSE28863_A4Up0.1744048716
GSE48662Down-0.3085889083

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-101-3pMIMAT0000099MIRT027343SequencingFunctional MTI (Weak)20371350
hsa-miR-19b-3pMIMAT0000074MIRT031221SequencingFunctional MTI (Weak)20371350
hsa-miR-26a-5pMIMAT0000082MIRT050110CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050526CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052333CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.