HCSGD entry for FNIP1
1. General information
| Official gene symbol | FNIP1 |
|---|---|
| Entrez ID | 96459 |
| Gene full name | folliculin interacting protein 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0001932 | Regulation of protein phosphorylation | IDA | biological_process |
| GO:0001934 | Positive regulation of protein phosphorylation | IMP | biological_process |
| GO:0002327 | Immature B cell differentiation | ISS | biological_process |
| GO:0002904 | Positive regulation of B cell apoptotic process | ISS | biological_process |
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0009267 | Cellular response to starvation | ISS | biological_process |
| GO:0031929 | TOR signaling | IMP | biological_process |
| GO:0032007 | Negative regulation of TOR signaling | ISS | biological_process |
| GO:0033138 | Positive regulation of peptidyl-serine phosphorylation | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0043154 | Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | ISS | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | IEA | biological_process |
| GO:2000973 | Regulation of pro-B cell differentiation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0486271646 | 0.9674300217 | 0.4864270209 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3468711007 |
| GSE13712_SHEAR | Up | 0.1567045805 |
| GSE13712_STATIC | Up | 0.1325293161 |
| GSE19018 | Down | -0.0588000653 |
| GSE19899_A1 | Up | 0.0385872783 |
| GSE19899_A2 | Up | 0.2050111561 |
| PubMed_21979375_A1 | Up | 0.1429957702 |
| PubMed_21979375_A2 | Up | 0.4774992004 |
| GSE35957 | Up | 0.0009073797 |
| GSE36640 | Down | -0.4682362237 |
| GSE54402 | Up | 0.4322361207 |
| GSE9593 | Up | 0.2136034763 |
| GSE43922 | Down | -0.0522832671 |
| GSE24585 | Up | 0.6519677001 |
| GSE37065 | Up | 0.3438247339 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.4374754303 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT021199 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040939 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047802 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049426 | CLASH//qRT-PCR | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052578 | CLASH | Functional MTI (Weak) | 23622248 |
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