HCSGD entry for CD53
1. General information
| Official gene symbol | CD53 |
|---|---|
| Entrez ID | 963 |
| Gene full name | CD53 molecule |
| Other gene symbols | MOX44 TSPAN25 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001772 | Immunological synapse | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0005911 | Cell-cell junction | ISS | cellular_component |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:1901741 | Positive regulation of myoblast fusion | ISS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9288833479 | 0.2099722579 | 0.9999902473 | 0.8851184817 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1506748047 |
| GSE13712_SHEAR | Down | -0.1511877705 |
| GSE13712_STATIC | Down | -0.0014845591 |
| GSE19018 | Up | 0.1929626908 |
| GSE19899_A1 | Up | 0.0516890091 |
| GSE19899_A2 | Up | 0.1143878663 |
| PubMed_21979375_A1 | Up | 0.0632222918 |
| PubMed_21979375_A2 | Up | 0.1593632833 |
| GSE35957 | Down | -0.0450681571 |
| GSE36640 | Up | 0.0895209136 |
| GSE54402 | Down | -0.0412365558 |
| GSE9593 | Down | -0.1110525861 |
| GSE43922 | Up | 0.0121964695 |
| GSE24585 | Down | -0.0068352959 |
| GSE37065 | Up | 0.0253728636 |
| GSE28863_A1 | Down | -0.7611074077 |
| GSE28863_A2 | Down | -0.6213025388 |
| GSE28863_A3 | Up | 0.0498011162 |
| GSE28863_A4 | Up | 0.0109099800 |
| GSE48662 | Down | -0.0909245492 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20225336 | In addition to elimination of intracellular aggregates and damaged organelles, autophagy promotes cellular senescence and cell surface antigen presentation, protects against genome instability and prevents necrosis, giving it a key role in preventing diseases such as cancer, neurodegeneration, cardiomyopathy, diabetes, liver disease, autoimmune diseases and infections |
| 17210617 | The paradox is that lymphocytes from RA patients are believed to resist apoptosis, and we suggest that the elevated expression of CD53, which results from the increased oxidative stress, may protect against apoptosis |
Entries Per Page
Displaying Page of
