HCSGD entry for RGS6

1. General information

Official gene symbolRGS6
Entrez ID9628
Gene full nameregulator of G-protein signaling 6
Other gene symbolsGAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004871Signal transducer activityIEAmolecular_function
GO:0005096GTPase activator activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0005834Heterotrimeric G-protein complexIEAcellular_component
GO:0005886Plasma membraneIBAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0008277Regulation of G-protein coupled receptor protein signaling pathwayTASbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0038032Termination of G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0043085Positive regulation of catalytic activityIBA TASbiological_process
GO:0043547Positive regulation of GTPase activityIBA TASbiological_process
GO:0045666Positive regulation of neuron differentiationIEAbiological_process
GO:0050790Regulation of catalytic activityIBA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87819689220.74483038260.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1055177473
GSE13712_SHEARUp0.0873326210
GSE13712_STATICDown-0.0317534448
GSE19018Up0.1079503977
GSE19899_A1Up0.0384163887
GSE19899_A2Up0.1166114796
PubMed_21979375_A1Down-0.0854550992
PubMed_21979375_A2Down-0.2358295834
GSE35957Down-0.0290772584
GSE36640Down-0.0352792839
GSE54402Up0.0046331070
GSE9593Up0.0119639825
GSE43922Up0.0437366793
GSE24585Up0.1020485692
GSE37065Down-0.0618484849
GSE28863_A1Down-0.1169368914
GSE28863_A2Down-0.0886151629
GSE28863_A3Up0.2262755203
GSE28863_A4Up0.0637737320
GSE48662Up0.0040856146

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.