HCSGD entry for MTRF1
1. General information
| Official gene symbol | MTRF1 |
|---|---|
| Entrez ID | 9617 |
| Gene full name | mitochondrial translational release factor 1 |
| Other gene symbols | MRF1 MTTRF1 RF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003747 | Translation release factor activity | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006449 | Regulation of translational termination | TAS | biological_process |
| GO:0016149 | Translation release factor activity, codon specific | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8851875917 | 0.2404034953 | 0.9999902473 | 0.9439418258 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0756701054 |
| GSE13712_SHEAR | Up | 0.1315215862 |
| GSE13712_STATIC | Up | 0.1599993617 |
| GSE19018 | Down | -0.2378098109 |
| GSE19899_A1 | Up | 0.0023879626 |
| GSE19899_A2 | Down | -0.2981136045 |
| PubMed_21979375_A1 | Up | 0.3398522682 |
| PubMed_21979375_A2 | Up | 0.0620454181 |
| GSE35957 | Down | -0.2757628077 |
| GSE36640 | Up | 0.0111233914 |
| GSE54402 | Down | -0.3502932868 |
| GSE9593 | Down | -0.2777618501 |
| GSE43922 | Up | 0.0500169343 |
| GSE24585 | Down | -0.1079535449 |
| GSE37065 | Up | 0.1746140823 |
| GSE28863_A1 | Up | 0.0025499663 |
| GSE28863_A2 | Down | -0.0415537905 |
| GSE28863_A3 | Down | -0.4024793842 |
| GSE28863_A4 | Up | 0.0499525526 |
| GSE48662 | Down | -0.2811876988 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040962 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050076 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
