HCSGD entry for GABBR2

1. General information

Official gene symbolGABBR2
Entrez ID9568
Gene full namegamma-aminobutyric acid (GABA) B receptor, 2
Other gene symbolsGABABR2 GPR51 GPRC3B HG20 HRIHFB2099
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004965G-protein coupled GABA receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007194Negative regulation of adenylate cyclase activityTASbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIDAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0038039G-protein coupled receptor heterodimeric complexIPIcellular_component
GO:0043005Neuron projectionIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08724417010.03830994260.61979859650.3682830898

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4828163292
GSE13712_SHEARDown-1.5380012919
GSE13712_STATICUp0.0746669456
GSE19018Up0.4336700700
GSE19899_A1Down-0.8472580327
GSE19899_A2Down-0.3861288036
PubMed_21979375_A1Down-0.1474870525
PubMed_21979375_A2Up0.1996520260
GSE35957Up0.8262160500
GSE36640Up0.7583138573
GSE54402Down-0.7441931095
GSE9593Up0.0372334365
GSE43922Down-0.0028165909
GSE24585Down-0.3032044748
GSE37065Up0.5563140505
GSE28863_A1Down-0.5033755819
GSE28863_A2Up0.0482109539
GSE28863_A3Up0.4868559373
GSE28863_A4Down-0.2115953168
GSE48662Down-0.4222556651

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

SGS742DB05010 -
ArbaclofenDB08891 -
Arbaclofen PlacarbilDB08892 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022745MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.