HCSGD entry for GTPBP1


1. General information

Official gene symbolGTPBP1
Entrez ID9567
Gene full nameGTP binding protein 1
Other gene symbolsGP-1 GP1 HSPC018
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000177Cytoplasmic exosome (RNase complex)IEA ISScellular_component
GO:0003924GTPase activityIEA ISSmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005829CytosolIEA ISScellular_component
GO:0006184GTP catabolic processISSbiological_process
GO:0006955Immune responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0061014Positive regulation of mRNA catabolic processIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14066414270.95652389350.75295618141.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0588725352
GSE13712_SHEARUp0.0791017721
GSE13712_STATICUp0.0732633940
GSE19018Up0.0789575544
GSE19899_A1Up0.1347005352
GSE19899_A2Up0.2269928449
PubMed_21979375_A1Up0.3456119836
PubMed_21979375_A2Up0.4958210367
GSE35957Down-0.1892528097
GSE36640Down-0.0657594753
GSE54402Up0.3146164360
GSE9593Down-0.0520873588
GSE43922Up0.0737615464
GSE24585Up0.1579403975
GSE37065Up0.3660714925
GSE28863_A1Up0.1510758073
GSE28863_A2Down-0.0867810548
GSE28863_A3Down-0.0729167495
GSE28863_A4Up0.1590024614
GSE48662Up0.3313592190

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027163SequencingFunctional MTI (Weak)20371350
hsa-miR-16-5pMIMAT0000069MIRT031922SequencingFunctional MTI (Weak)20371350
hsa-miR-423-5pMIMAT0004748MIRT038114CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041906CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043448CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048537CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.