HCSGD entry for VPS26A


1. General information

Official gene symbolVPS26A
Entrez ID9559
Gene full namevacuolar protein sorting 26 homolog A (S. pombe)
Other gene symbolsHB58 Hbeta58 PEP8A VPS26
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005768EndosomeIDA IEAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0007034Vacuolar transportIEAbiological_process
GO:0008565Protein transporter activityNASmolecular_function
GO:0010008Endosome membraneIEAcellular_component
GO:0030904Retromer complexIEAcellular_component
GO:0031982VesicleIDAcellular_component
GO:0042147Retrograde transport, endosome to GolgiIEA NASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49443393490.85119732150.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1518880483
GSE13712_SHEARUp0.3123359482
GSE13712_STATICUp0.1212459625
GSE19018Down-0.0619470159
GSE19899_A1Up0.0195121869
GSE19899_A2Down-0.0292831247
PubMed_21979375_A1Down-0.1298841060
PubMed_21979375_A2Down-0.0342658064
GSE35957Down-0.0793364625
GSE36640Up0.0153770452
GSE54402Up0.0971652493
GSE9593Up0.2340820174
GSE43922Down-0.0625648681
GSE24585Up0.1330163079
GSE37065Up0.0401903999
GSE28863_A1Up0.0429943241
GSE28863_A2Up0.3261290433
GSE28863_A3Down-0.1949321103
GSE28863_A4Up0.1710234274
GSE48662Down-0.2368155522

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-373-3pMIMAT0000726MIRT004448MicroarrayFunctional MTI (Weak)15685193
hsa-miR-7-5pMIMAT0000252MIRT025885MicroarrayFunctional MTI (Weak)17612493
hsa-miR-7-5pMIMAT0000252MIRT025885MicroarrayFunctional MTI (Weak)19073608
hsa-miR-21-5pMIMAT0000076MIRT031005MicroarrayFunctional MTI (Weak)18591254
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-373-3pMIMAT0000726NAhsa-miR-37315685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

25412306We identified 107 proteins that could be potential markers of senescence and validated 10 of them (DEP1, NTAL, EBP50, STX4, VAMP3, ARMX3, B2MG, LANCL1, VPS26A and PLD3)
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