HCSGD entry for APBA3


1. General information

Official gene symbolAPBA3
Entrez ID9546
Gene full nameamyloid beta (A4) precursor protein-binding, family A, member 3
Other gene symbolsMGC:15815 X11L2 mint3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001540Beta-amyloid bindingIEAmolecular_function
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0004857Enzyme inhibitor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0007268Synaptic transmissionIEAbiological_process
GO:0010468Regulation of gene expressionIEAbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0043086Negative regulation of catalytic activityIDAbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10793231640.93609003840.68219913651.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2952438695
GSE13712_SHEARUp0.1160216799
GSE13712_STATICUp0.3122465454
GSE19018Up0.0682539737
GSE19899_A1Up0.0947682112
GSE19899_A2Up0.2339536613
PubMed_21979375_A1Up0.7196957749
PubMed_21979375_A2Up1.0208464410
GSE35957Up0.0085474698
GSE36640Up0.1005900943
GSE54402Up0.0938445030
GSE9593Up0.0360417192
GSE43922Up0.1542640305
GSE24585Down-0.1317609475
GSE37065Up0.0240593421
GSE28863_A1Down-0.0757257879
GSE28863_A2Down-0.2219257296
GSE28863_A3Up0.0606774402
GSE28863_A4Down-0.1575186202
GSE48662Up0.3844420889

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT040391CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048517CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.