HCSGD entry for APBA3
1. General information
| Official gene symbol | APBA3 |
|---|---|
| Entrez ID | 9546 |
| Gene full name | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| Other gene symbols | MGC:15815 X11L2 mint3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001540 | Beta-amyloid binding | IEA | molecular_function |
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0004857 | Enzyme inhibitor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0007268 | Synaptic transmission | IEA | biological_process |
| GO:0010468 | Regulation of gene expression | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0043086 | Negative regulation of catalytic activity | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1079323164 | 0.9360900384 | 0.6821991365 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2952438695 |
| GSE13712_SHEAR | Up | 0.1160216799 |
| GSE13712_STATIC | Up | 0.3122465454 |
| GSE19018 | Up | 0.0682539737 |
| GSE19899_A1 | Up | 0.0947682112 |
| GSE19899_A2 | Up | 0.2339536613 |
| PubMed_21979375_A1 | Up | 0.7196957749 |
| PubMed_21979375_A2 | Up | 1.0208464410 |
| GSE35957 | Up | 0.0085474698 |
| GSE36640 | Up | 0.1005900943 |
| GSE54402 | Up | 0.0938445030 |
| GSE9593 | Up | 0.0360417192 |
| GSE43922 | Up | 0.1542640305 |
| GSE24585 | Down | -0.1317609475 |
| GSE37065 | Up | 0.0240593421 |
| GSE28863_A1 | Down | -0.0757257879 |
| GSE28863_A2 | Down | -0.2219257296 |
| GSE28863_A3 | Up | 0.0606774402 |
| GSE28863_A4 | Down | -0.1575186202 |
| GSE48662 | Up | 0.3844420889 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040391 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048517 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
