HCSGD entry for NRG2
1. General information
| Official gene symbol | NRG2 |
|---|---|
| Entrez ID | 9542 |
| Gene full name | neuregulin 2 |
| Other gene symbols | DON1 HRG2 NTAK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | IEA TAS | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | TAS | biological_process |
| GO:0009790 | Embryo development | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3489268341 | 0.9191632613 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0224316526 |
| GSE13712_SHEAR | Up | 0.2297778883 |
| GSE13712_STATIC | Up | 0.0787773561 |
| GSE19018 | Up | 0.0825732479 |
| GSE19899_A1 | Up | 0.0305897637 |
| GSE19899_A2 | Down | -0.0507206578 |
| PubMed_21979375_A1 | Down | -0.0402867054 |
| PubMed_21979375_A2 | Down | -0.0168407627 |
| GSE35957 | Up | 0.1612264783 |
| GSE36640 | Up | 0.0618912311 |
| GSE54402 | Up | 0.0063555898 |
| GSE9593 | Up | 0.0397148983 |
| GSE43922 | Up | 0.0664162385 |
| GSE24585 | Down | -0.0374903908 |
| GSE37065 | Up | 0.0415523469 |
| GSE28863_A1 | Down | -0.2372726078 |
| GSE28863_A2 | Up | 0.0461740970 |
| GSE28863_A3 | Up | 0.3881112368 |
| GSE28863_A4 | Up | 0.1678350432 |
| GSE48662 | Up | 0.4320562838 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
