HCSGD entry for SCARB2
1. General information
| Official gene symbol | SCARB2 |
|---|---|
| Entrez ID | 950 |
| Gene full name | scavenger receptor class B, member 2 |
| Other gene symbols | AMRF CD36L2 EPM4 HLGP85 LGP85 LIMP-2 LIMPII SR-BII |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0005765 | Lysosomal membrane | IDA ISS | cellular_component |
| GO:0006622 | Protein targeting to lysosome | IMP | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0043202 | Lysosomal lumen | ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8685829034 | 0.0308957144 | 0.9999902473 | 0.3311875101 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2103121458 |
| GSE13712_SHEAR | Down | -0.0125848544 |
| GSE13712_STATIC | Down | -0.0603490272 |
| GSE19018 | Down | -0.2849938079 |
| GSE19899_A1 | Down | -0.7909619916 |
| GSE19899_A2 | Down | -0.5831987879 |
| PubMed_21979375_A1 | Down | -1.0417164559 |
| PubMed_21979375_A2 | Down | -0.5644326217 |
| GSE35957 | Down | -0.0352645021 |
| GSE36640 | Up | 0.2086953355 |
| GSE54402 | Down | -0.5384211113 |
| GSE9593 | Up | 0.6583281853 |
| GSE43922 | Down | -0.1049809413 |
| GSE24585 | Up | 0.1127702787 |
| GSE37065 | Up | 0.3775343486 |
| GSE28863_A1 | Up | 0.2599420198 |
| GSE28863_A2 | Up | 0.3193838593 |
| GSE28863_A3 | Down | -0.5389326921 |
| GSE28863_A4 | Down | -0.3352803581 |
| GSE48662 | Down | -0.0197154297 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025719 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025719 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-365a-3p | MIMAT0000710 | MIRT044021 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046711 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049516 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
