HCSGD entry for PGS1
1. General information
| Official gene symbol | PGS1 |
|---|---|
| Entrez ID | 9489 |
| Gene full name | phosphatidylglycerophosphate synthase 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | ISS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | ISS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006655 | Phosphatidylglycerol biosynthetic process | ISS TAS | biological_process |
| GO:0008444 | CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity | ISS | molecular_function |
| GO:0008654 | Phospholipid biosynthetic process | IEA | biological_process |
| GO:0016780 | Phosphotransferase activity, for other substituted phosphate groups | IEA | molecular_function |
| GO:0032049 | Cardiolipin biosynthetic process | ISS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046339 | Diacylglycerol metabolic process | ISS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0573007712 | 0.9751754911 | 0.5200736552 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3541026128 |
| GSE13712_SHEAR | Up | 0.8745206888 |
| GSE13712_STATIC | Up | 0.3615488751 |
| GSE19018 | Up | 0.0412949117 |
| GSE19899_A1 | Up | 0.0726602791 |
| GSE19899_A2 | Up | 0.4116269821 |
| PubMed_21979375_A1 | Down | -0.2659069816 |
| PubMed_21979375_A2 | Up | 0.4818887992 |
| GSE35957 | Down | -0.0481481289 |
| GSE36640 | Up | 0.1432655641 |
| GSE54402 | Down | -0.0303278616 |
| GSE9593 | Down | -0.1142748289 |
| GSE43922 | Up | 0.2673356276 |
| GSE24585 | Up | 0.2546744149 |
| GSE37065 | Down | -0.1933181390 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.5216643089 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016033 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
