HCSGD entry for ONECUT2
1. General information
| Official gene symbol | ONECUT2 |
|---|---|
| Entrez ID | 9480 |
| Gene full name | one cut homeobox 2 |
| Other gene symbols | OC-2 OC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001889 | Liver development | IEA | biological_process |
| GO:0001952 | Regulation of cell-matrix adhesion | IEA | biological_process |
| GO:0002064 | Epithelial cell development | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0009887 | Organ morphogenesis | TAS | biological_process |
| GO:0030335 | Positive regulation of cell migration | IEA | biological_process |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | IEA | biological_process |
| GO:0031018 | Endocrine pancreas development | IEA | biological_process |
| GO:0042384 | Cilium assembly | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045165 | Cell fate commitment | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0048935 | Peripheral nervous system neuron development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8064047035 | 0.7512912731 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0432667856 |
| GSE13712_SHEAR | Down | -0.0791604900 |
| GSE13712_STATIC | Up | 0.1218752500 |
| GSE19018 | Up | 0.1509924282 |
| GSE19899_A1 | Down | -0.0324475478 |
| GSE19899_A2 | Up | 0.1159332400 |
| PubMed_21979375_A1 | Up | 0.0614963250 |
| PubMed_21979375_A2 | Up | 0.0656094944 |
| GSE35957 | Up | 0.0336370348 |
| GSE36640 | Up | 0.0042588078 |
| GSE54402 | Up | 0.0223071667 |
| GSE9593 | Up | 0.0196971690 |
| GSE43922 | Up | 0.0386442176 |
| GSE24585 | Down | -0.3029668962 |
| GSE37065 | Down | -0.0365543324 |
| GSE28863_A1 | Down | -0.1367315808 |
| GSE28863_A2 | Down | -0.0364239843 |
| GSE28863_A3 | Up | 0.2988466036 |
| GSE28863_A4 | Down | -0.0877239589 |
| GSE48662 | Up | 0.0784401694 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT005390 | Luciferase reporter assay//Northern blot//qRT-PCR//Western blot | Functional MTI | 16831872 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT005390 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031575 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032175 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
