HCSGD entry for MED20
1. General information
| Official gene symbol | MED20 |
|---|---|
| Entrez ID | 9477 |
| Gene full name | mediator complex subunit 20 |
| Other gene symbols | PRO0213 TRFP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001104 | RNA polymerase II transcription cofactor activity | IEA | molecular_function |
| GO:0003899 | DNA-directed RNA polymerase activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | NAS | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016592 | Mediator complex | IEA NAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9907636564 | 0.0153100718 | 0.9999902473 | 0.2430496984 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0310106541 |
| GSE13712_SHEAR | Up | 0.2722089072 |
| GSE13712_STATIC | Up | 0.1189497846 |
| GSE19018 | Up | 0.0857135118 |
| GSE19899_A1 | Down | -0.3846082858 |
| GSE19899_A2 | Down | -0.7475452868 |
| PubMed_21979375_A1 | Down | -1.6789839614 |
| PubMed_21979375_A2 | Down | -1.0055080475 |
| GSE35957 | Down | -0.3786166497 |
| GSE36640 | Down | -0.3717322591 |
| GSE54402 | Down | -0.4735796265 |
| GSE9593 | Up | 0.0288074280 |
| GSE43922 | Down | -0.5018783312 |
| GSE24585 | Down | -0.2489559269 |
| GSE37065 | Down | -0.2312817796 |
| GSE28863_A1 | Down | -0.0797578747 |
| GSE28863_A2 | Up | 0.0127986104 |
| GSE28863_A3 | Down | -0.3539843628 |
| GSE28863_A4 | Down | -0.1450456610 |
| GSE48662 | Down | -0.0300302277 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022390 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
