HCSGD entry for CHST3


1. General information

Official gene symbolCHST3
Entrez ID9469
Gene full namecarbohydrate (chondroitin 6) sulfotransferase 3
Other gene symbolsC6ST C6ST1 HSD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006790Sulfur compound metabolic processIDAbiological_process
GO:0008146Sulfotransferase activityTASmolecular_function
GO:0008459Chondroitin 6-sulfotransferase activityIDAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030204Chondroitin sulfate metabolic processTASbiological_process
GO:0030206Chondroitin sulfate biosynthetic processIDA TASbiological_process
GO:0043029T cell homeostasisIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050698Proteoglycan sulfotransferase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08697040770.29918133430.61878905411.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0307434934
GSE13712_SHEARDown-0.5949251530
GSE13712_STATICDown-0.2909785363
GSE19018Down-0.2877326598
GSE19899_A1Down-0.1016801080
GSE19899_A2Down-0.4757572868
PubMed_21979375_A1Up0.3621013231
PubMed_21979375_A2Up0.9264214955
GSE35957Down-0.3252015290
GSE36640Up1.3119015397
GSE54402Down-0.3601462079
GSE9593Up0.0813661317
GSE43922Up0.1896505981
GSE24585Down-0.2061067752
GSE37065Down-0.0783724261
GSE28863_A1Up0.8971029977
GSE28863_A2Up0.4974374597
GSE28863_A3Up0.3689202323
GSE28863_A4Down-0.0138188827
GSE48662Up0.2256453166

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-122-5pMIMAT0000421MIRT023379MicroarrayFunctional MTI (Weak)17612493
hsa-miR-98-5pMIMAT0000096MIRT027845MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

18024225Gene expression of types I, II, and VI collagen, aggrecan, and chondroitin-6-sulfotransferase in the human annulus: in situ hybridization findings
18024225PURPOSE: To determine the percentage and patterns of gene expression for types I, II, and VI collagen, aggrecan, and chondroitin-6-sulfotransferase in the human annulus
18024225OUTCOME MEASURES: The percentages of cells in the human annulus expressing type I, II, and VI collagen, aggrecan, and chondroitin-6-sulfotransferase
180242257% chondroitin-6-sulfotransferase
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