HCSGD entry for SH3BP5
1. General information
| Official gene symbol | SH3BP5 |
|---|---|
| Entrez ID | 9467 |
| Gene full name | SH3-domain binding protein 5 (BTK-associated) |
| Other gene symbols | SAB SH3BP-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004860 | Protein kinase inhibitor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006469 | Negative regulation of protein kinase activity | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1403116599 | 0.6993797690 | 0.7527260444 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0369053197 |
| GSE13712_SHEAR | Up | 0.0296635370 |
| GSE13712_STATIC | Up | 0.0793142009 |
| GSE19018 | Down | -0.2079077178 |
| GSE19899_A1 | Up | 0.2666664660 |
| GSE19899_A2 | Up | 0.1185634830 |
| PubMed_21979375_A1 | Down | -0.3225958971 |
| PubMed_21979375_A2 | Up | 0.1781135629 |
| GSE35957 | Up | 0.2200585556 |
| GSE36640 | Up | 0.6696760413 |
| GSE54402 | Up | 0.0904604637 |
| GSE9593 | Up | 0.0266530712 |
| GSE43922 | Down | -0.0537473386 |
| GSE24585 | Down | -0.2348135642 |
| GSE37065 | Up | 0.1372227764 |
| GSE28863_A1 | Up | 0.3165287637 |
| GSE28863_A2 | Up | 0.4073003348 |
| GSE28863_A3 | Down | -0.0185947866 |
| GSE28863_A4 | Down | -0.2462538949 |
| GSE48662 | Up | 0.6319296056 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020283 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027201 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041600 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
