HCSGD entry for IL27RA
1. General information
| Official gene symbol | IL27RA |
|---|---|
| Entrez ID | 9466 |
| Gene full name | interleukin 27 receptor, alpha |
| Other gene symbols | CRL1 IL-27RA IL27R TCCR WSX1 zcytor1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002827 | Positive regulation of T-helper 1 type immune response | IEA | biological_process |
| GO:0002829 | Negative regulation of type 2 immune response | IEA | biological_process |
| GO:0004888 | Transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0032729 | Positive regulation of interferon-gamma production | IEA | biological_process |
| GO:0045509 | Interleukin-27 receptor activity | IEA | molecular_function |
| GO:0048302 | Regulation of isotype switching to IgG isotypes | IEA | biological_process |
| GO:0050830 | Defense response to Gram-positive bacterium | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1486282512 | 0.8325290908 | 0.7716063511 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0929421147 |
| GSE13712_SHEAR | Up | 0.5138474391 |
| GSE13712_STATIC | Up | 0.6768161184 |
| GSE19018 | Down | -0.1939928536 |
| GSE19899_A1 | Up | 0.1140923324 |
| GSE19899_A2 | Up | 0.5074863254 |
| PubMed_21979375_A1 | Up | 0.2997003555 |
| PubMed_21979375_A2 | Up | 0.5572442230 |
| GSE35957 | Down | -0.3180273308 |
| GSE36640 | Down | -0.0653626446 |
| GSE54402 | Up | 0.0157540326 |
| GSE9593 | Down | -0.1741158886 |
| GSE43922 | Up | 0.1920030846 |
| GSE24585 | Up | 0.5715963572 |
| GSE37065 | Down | -0.0867327965 |
| GSE28863_A1 | Down | -0.1787822506 |
| GSE28863_A2 | Down | -0.0138826396 |
| GSE28863_A3 | Down | -0.0394884890 |
| GSE28863_A4 | Up | 0.0283187875 |
| GSE48662 | Up | 0.0339783857 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022747 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023830 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
