HCSGD entry for RASAL2
1. General information
| Official gene symbol | RASAL2 |
|---|---|
| Entrez ID | 9462 |
| Gene full name | RAS protein activator like 2 |
| Other gene symbols | NGAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005099 | Ras GTPase activator activity | IBA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0031235 | Intrinsic component of the cytoplasmic side of the plasma membrane | IBA | cellular_component |
| GO:0032320 | Positive regulation of Ras GTPase activity | IBA | biological_process |
| GO:0046580 | Negative regulation of Ras protein signal transduction | IBA | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5282750237 | 0.4245591581 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0923850116 |
| GSE13712_SHEAR | Up | 0.0246132110 |
| GSE13712_STATIC | Down | -0.0597254497 |
| GSE19018 | Up | 0.0906180180 |
| GSE19899_A1 | Down | -0.0589831644 |
| GSE19899_A2 | Down | -0.0187857097 |
| PubMed_21979375_A1 | Down | -0.5037872888 |
| PubMed_21979375_A2 | Up | 0.1937776811 |
| GSE35957 | Up | 0.2523367103 |
| GSE36640 | Up | 0.0878872470 |
| GSE54402 | Down | -0.1268377180 |
| GSE9593 | Up | 0.3090229819 |
| GSE43922 | Down | -0.0276190367 |
| GSE24585 | Down | -0.0066878763 |
| GSE37065 | Up | 0.1897070657 |
| GSE28863_A1 | Up | 0.3044452363 |
| GSE28863_A2 | Up | 0.6523224494 |
| GSE28863_A3 | Down | -0.5777916756 |
| GSE28863_A4 | Down | -0.2746768699 |
| GSE48662 | Down | -0.0576479451 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027468 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029026 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-15a-3p | MIMAT0004488 | MIRT038984 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045969 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048603 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048987 | CLASH//qRT-PCR | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
