HCSGD entry for MAP4K4
1. General information
| Official gene symbol | MAP4K4 |
|---|---|
| Entrez ID | 9448 |
| Gene full name | mitogen-activated protein kinase kinase kinase kinase 4 |
| Other gene symbols | FLH21957 HGK MEKKK4 NIK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0004702 | Receptor signaling protein serine/threonine kinase activity | IBA | molecular_function |
| GO:0005083 | Small GTPase regulator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0016772 | Transferase activity, transferring phosphorus-containing groups | IEA | molecular_function |
| GO:0023014 | Signal transduction by phosphorylation | IBA | biological_process |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
| GO:0046328 | Regulation of JNK cascade | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0075899016 | 0.9591381065 | 0.2270156818 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5042425180 |
| GSE13712_SHEAR | Up | 0.7353362619 |
| GSE13712_STATIC | Up | 0.3022101483 |
| GSE19018 | Down | -0.3343981499 |
| GSE19899_A1 | Up | 1.0304947701 |
| GSE19899_A2 | Up | 0.3379881680 |
| PubMed_21979375_A1 | Down | -0.4030226791 |
| PubMed_21979375_A2 | Up | 0.3005661177 |
| GSE35957 | Down | -0.2538908589 |
| GSE36640 | Up | 0.1377099121 |
| GSE54402 | Up | 0.5524196756 |
| GSE9593 | Up | 0.2509291357 |
| GSE43922 | Up | 0.4876457356 |
| GSE24585 | Up | 0.0799619436 |
| GSE37065 | Down | -0.1051096918 |
| GSE28863_A1 | Up | 0.8840660245 |
| GSE28863_A2 | Up | 0.8179870564 |
| GSE28863_A3 | Up | 0.1689345240 |
| GSE28863_A4 | Down | -0.0531795545 |
| GSE48662 | Down | -0.3508747694 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
