HCSGD entry for MED26


1. General information

Official gene symbolMED26
Entrez ID9441
Gene full namemediator complex subunit 26
Other gene symbolsCRSP7 CRSP70
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001104RNA polymerase II transcription cofactor activityIDAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003713Transcription coactivator activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016592Mediator complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41489680480.93389771290.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0404764701
GSE13712_SHEARUp0.1537212458
GSE13712_STATICUp0.1102364120
GSE19018Down-0.0506654021
GSE19899_A1Up0.1319669100
GSE19899_A2Up0.3833792927
PubMed_21979375_A1Down-0.0208597078
PubMed_21979375_A2Up0.2561411899
GSE35957Up0.0043461902
GSE36640Down-0.0276785132
GSE54402Down-0.0149825368
GSE9593Up0.1389520473
GSE43922Up0.1068902308
GSE24585Up0.1205550156
GSE37065Down-0.1005349587
GSE28863_A1Up0.0636609780
GSE28863_A2Up0.0501023474
GSE28863_A3Up0.1041290355
GSE28863_A4Down-0.0531065078
GSE48662Up0.0237740481

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-320aMIMAT0000510MIRT044629CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.